Excerpts from BBC News:
Amie had first developed a problem with her eye when she was pregnant with Lee in 2002.
Lee was born that August and by December a skin cancer had spread to the back of Amie's eye and to her liver.
She had terminal cancer and was initially given just 12 months to live, but she battled on for two and a half years.
Deborah and Lee Deborah Hughes now looks after her grandson Lee.
Her mother, also from Rhayader, has said it was because she did not want to leave her son.
"The hardest part of the treatment for her was not having the energy to play with Lee," said her mother.
"Lee was the reason she survived so long," she added. "Her sheer guts and determination - she just didn't want to leave him.
Jo Checkley, editor of magazine That's Life, which awarded the Single Mum of the Year prizes, said: "Amie's death moved us to tears.
"It was a deep, deep tragedy and we feel humbled and honoured to award this prize in Amie's memory to her mother Deborah.
"As Lee grows up he will realise what an incredibly brave mum he had."
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