Ok, so it's not exactly a cure but...

Researchers from the National Cancer Institute (NCI) recently discovered a new way to use gene therapy to shrink tumours. Of the 17 people treated in the clinical trial, two were in remission with no signs of the disease. Unfortunately the other 15 died so there is still a lot of work to do. According to the American Cancer Society, this is the first evidence that gene therapy can actually fight cancer.

NCI Press Release

A team of researchers at the National Cancer Institute (NCI), part of the National Institutes of Health, has demonstrated sustained regression of advanced melanoma in a study of 17 patients by genetically engineering patients' own white blood cells to recognize and attack cancer cells. The study appears in the online edition of the journal Science on August 31, 2006*.

"These results represent the first time gene therapy has been used successfully to treat cancer. Moreover, we hope it will be applicable not only to melanoma, but also for a broad range of common cancers, such as breast and lung cancer," said NIH Director Elias A. Zerhouni, M.D.

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For a Q &A on gene therapy techniques similar to those used in this study, go to: http://www.cancer.gov/cancertopics/factsheet/Therapy/gene.

For more information on Dr. Rosenberg's research, go to http://ccr.cancer.gov/staff/staff.asp?profileid=5757.

* Morgan RA, Dudley ME, Wunderlich JR, Hughes MS, Yang JC, Sherry RM, Royal RE, Topalian SL, Kammula US, Restifo NP, Zheng Z, Nahvi A, de Vries CR, Rogers-Freezer LJ, Mavroukakis SA, Rosenberg SA. Cancer regression in patients mediated by transfer of genetically engineered lymphocytes. Science Express. Online August 31, 2006.


**UPDATE 9/9/06**
National Public Radio did a story on gene therapy recently which includes an interview with NCI researcher, Dr. Steven Rosenberg. You can listen to it here.